Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock

DOI: 10.1021/jacs.0c12280

Source and publish data:

Journal of the American Chemical Society p. 2078 - 2087 (2021)

Update date:2022-08-05

Topics:

Authors:

Kolarski, Du?an

Miller, Simon

Oshima, Tsuyoshi

Nagai, Yoshiko

Aoki, Yugo

Kobauri, Piermichele

Srivastava, Ashutosh

Sugiyama, Akiko

Amaike, Kazuma

Sato, Ayato

Tama, Florence

Szymanski, Wiktor

Feringa, Ben L.

Itami, Kenichiro

Hirota, Tsuyoshi

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Article abstract of DOI:10.1021/jacs.0c12280

CRY1 and CRY2 proteins are highly conserved components of the circadian clock that controls daily physiological rhythms. Disruption of CRY functions are related to many diseases, including circadian sleep phase disorder. Development of isoform-selective a

Full text of DOI:10.1021/jacs.0c12280

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