Synthesis and synthetic applications of 3-amino-Δ5-piperidein-2-ones: Synthesis of methionine-derived pseudopeptides

Article abstract of DOI:10.1016/S0040-4020(99)00545-1

A method is described for the efficient preparation of 3-amino-Δ⁵- piperidein-2-ones 3. A synthetic application of enamides 3 has been achieved by methylthiolation on the C5 position to obtain the target methionine- derived pseudopeptides 2.