Journal of Medicinal Chemistry p. 1828 - 1832 (1985)
Update date:2022-07-30
Topics:
Spencer, Robin W.
Copp, Leslie J.
Pfister, Juerg R.
Elasnin and 15 related 4-hydroxy-2-pyrones have been assayed for in vitro inhibition of human leukocyte elastase, porcine pancreatic elastase, and bovine chymotrypsin.Inhibition constants for HL elastase range from 0.1 to 10 mM.The principal determinant o
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