Journal of the American Chemical Society p. 7778 - 7786 (1999)
Update date:2022-07-31
Topics:
Snider, Barry B.
Lin, Hong
The first synthesis of the immunosuppressant (-)-FR901483 (1) has been accomplished in 2% overall yield from O-methyltyrosine methyl ester (31) in 22 steps establishing the absolute stereochemistry of the natural product. A 1,3-dipolar cycloaddition of ni
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Doi:10.1021/ie50586a034
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(1999)Doi:10.1039/a903262b
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