Triflates as synthons for the synthesis of lysine analogues

Article abstract of DOI:10.1016/S0040-4039(99)01445-8

A simple synthesis of various 6-amino-2-substituted hexanoic acids has been developed starting from lysine via the triflate of 6-amino-2-hydroxy hexanoic acid. The same reactions have also been successfully applied starting from the lysyl-proline sequence