Phosphorodithioates: Synthesis and evaluation of new haptens for the generation of antibody acyl transferases

DOI: 10.1016/S0040-4039(99)01501-4

Source and publish data:

Tetrahedron Letters p. 7307 - 7310 (1999)

Update date:2022-08-05

Topics:

Authors:

Bruemmer, Oliver

Wentworth Jr., Paul

Weiner, David P.

Janda, Kim D.

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Article abstract of DOI:10.1016/S0040-4039(99)01501-4

An extension of the transition state analogue (TSA) hapten approach for the elicitation of catalytic antibodies for acyl-transfer reactions is described. It is based on the enlistment of phosphorodithioate 1 as a stable mimic of the putative tetrahedral i

Full text of DOI:10.1016/S0040-4039(99)01501-4

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