A facile and practical synthesis of capsazepine, a vanilloid receptor antagonist

Article abstract of DOI:10.1080/00397919908085886

A facile and practical synthesis of capsazepine, a vanilloid receptor antagonist, has been accomplished from isovanillin in 8 steps via an efficient intramolecular Mannich cyclization.

Full text of DOI:10.1080/00397919908085886

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic Organic
Chemistry
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A Facile and Practical Synthesis of
Capsazepine, a Vanilloid Receptor
Antagonist
Jeewoo Lee a & Jiyoun Lee a
a Laboratory of Medicinal Chemistry, College of Pharmacy,
Seoul National University, Shinlim-Dong, Kwanak-Ku, Seoul,
151-742, Korea
Version of record first published: 17 Sep 2007.
To cite this article: Jeewoo Lee & Jiyoun Lee (1999): A Facile and Practical Synthesis of
Capsazepine, a Vanilloid Receptor Antagonist, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 29:23, 4127-4140
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