A direct anionic cyclization of 2-alkynylbenzonitrile to 3- substituted-1(2H)-isoquinolones and 3-benzylideneisoindol-2ones initiated by methoxide addition

DOI: 10.1016/S0040-4020(99)00812-1

Source and publish data:

Tetrahedron p. 13193 - 13200 (1999)

Update date:2022-07-30

Topics:

Authors:

Wu, Ming-Jung

Chang, Li-Juan

Wei, Li-Mei

Lin, Chi-Fong

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(99)00812-1

Treatment of 2-(2-alkylethynyl)benzonitrile with sodium methoxide in refluxing methanol for 12 h gave 3-alkyl-1(2H)- isoquinolone in modest yield. Under the same reaction conditions, methanolysis of 2-(2-arylethynyl)benzonitrile lead to the formation of 3

Full text of DOI:10.1016/S0040-4020(99)00812-1

Products guided by the article

Product name:2-(3-phenyl-1-propynyl)-1-iodobenzene

Cas No:253435-17-5

R&D Labs maybe for 253435-17-5

DU-HOPE INTERNATIONAL GROUP

Contact:+86-25-52346955

Address:199,JIANYE ROAD,NANJING,CHINA
Shanghai UCHEM Inc.

Contact:+86-21-56338808

Address:799 Dunhuang Road, Putuo
ZHEJIANG SYNOSE TECH CO.,LTD.

website:https://www.synose.com/

Contact:86-579-82275537

Address:No.1958 Liyu Road , jinhua,zhejiang,China
Phantom-pharma

Contact:

Address:
Anhui Xinyuan Technology Co.,Ltd

Contact:0086-559-3515800

Address:No.16 Zijin Rd, Circular Economic Zone, Huizhou District, Huangshan Anhui China

Relevant to this article

Doi:10.1139/v69-204
(1969)
Complete structures of the sphingosine analog mycotoxins fumonisin B₁ and AAL toxin T(A): Absolute configuration of the side chains

Doi:10.1016/0040-4039(95)00090-Y
(1995)
Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates

Doi:10.1016/j.bmc.2015.04.069
(2015)
Doi:10.1039/c29710000559
(1971)
Xanthone-2-carboxylic acids, a new series of antiallergic substances.

Doi:10.1021/jm00280a010
(1972)
Doi:10.1016/S0040-4020(01)97763-4
(1971)

Article Doi