Bioorganic and Medicinal Chemistry Letters p. 3133 - 3136 (1999)
Update date:2022-08-03
Topics:
Martinez, Ana
Gil, Carmen
Perez, Concepcion
Castro, Ana
Prieto, Columbiana
Otero, Joaquin
Modifications of our previously reported lead compounds, acyclonucleosides derived from 2,1,3-benzothiadiazine dioxides, in the search for inhibitors of human cytomegalovirus (HCMV), lead us to identify the chlorophenylmethyl benzothiadiazine dioxides derivatives as potent HCMV inhibitors. The synthesis and antiviral data of this second-generation of benzothiadiazine dioxide compounds are reported.
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