Synthesis of an iodine-labelled analogue of practolol: (S)-3-[4-(4-iodobut-3-encarboxamido)phenoxy]-1-isopropylaminoepropan-2-ol (AMI-9S)

DOI: 10.1002/(SICI)1099-1344(199912)42:12<1195::AID-JLCR275>3.0.CO;2-R

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 1195 - 1202 (1999)

Update date:2022-08-04

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Authors:

Apparu, Marcel

Ben Tiba, Younes

Leo, Pierre-Marc

Mathieu, Jean Paul

Mauclaire, Laurent

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Article abstract of DOI:10.1002/(SICI)1099-1344(199912)42:12<1195::AID-JLCR275>3.0.CO;2-R

AMI-9S was synthesized in the S configuration with an enantiomeric purity of over 97% and labelled with iodine-123 with a specific activity of 300 Ci/mmol. Enantiomeric purity was determined by ¹⁹F NMR spectroscopy following derivatisation usin

Full text of DOI:10.1002/(SICI)1099-1344(199912)42:12<1195::AID-JLCR275>3.0.CO;2-R

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Product name:(S)-3-[4-[(5-iodo-4-pentenoyl)amino]phenoxy]-1-(isopropylamino)propan-2-ol

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