Synthesis, dopamine and serotonin transporter binding affinities of novel analogues of meperidine

Article abstract of DOI:10.1016/S0960-894X(99)00606-X

A series of meperidine analogues was synthesized and the binding affinities for the dopamine and serotonin transporters were determined. The substituents on the phenyl ring greatly influenced the potency and selectivity of these compounds for the transpor