Tetrahedron Letters p. 8805 - 8809 (1999)
Update date:2022-08-04
Topics:
Chassaing, Christophe
Haudrechy, Arnaud
Langlois, Yves
A new formal stereoselective synthesis of (+)-huperzine A 1 was achieved using as a key step a palladium mediated annulation between 2-methylene-1,3- propanediol diacetate and (1R,2S)-2-phenylcyclohexanol derived β-ketoester 14.
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