New approach to the stereoselective synthesis of the [4.5] spiroketal moiety of papulacandins

Article abstract of DOI:10.1016/s0040-4020(99)00990-4

An efficient approach for the stereoselective construction of the spiroketal moiety of papulacandins, based on the condensation of the protected derivative of D-arabino-1,4-lactone 2 with the α-lithiated carbanion of β-phenylsulfonyl dihydrofuran 1, is de