N-OXIDES OF HOMOAPORPHINE ALKALOIDS FROM MERENDERA RADDEANA

Article abstract of DOI:10.1007/BF00629836

The alkaloid complex of the leaves, stems, seeds, and seed pods of Merendera raddeana Rgl. (family Liliaceae) has been investigated.A number of known tropolone alkaloids and their photochemical isomers have been isolated together with the homoaporphine bases merenderine, kreysigenine, and O-methylkreysigenine and their N-oxides, which have not been described in the literature.One of them (merenderine N-oxide) has been characterized by its physical constants and has been investigated by IR, PMR, and mass-spectral methods.By a study of the PMR spectrum of the fraction of neutral alkaloids from the leaves of the plant it has been established that it consists mainly of a mixture of equal amounts of colchicine and cornigerine.