Chemistry of Heterocyclic Compounds p. 167 - 175 (1995)
Update date:2022-08-04
Topics:
Ukrainets, I. V.
Taran, S. G.
Gorokhova, O. V.
Marusenko, N. A.
Kovalenko, S. N.
et al.
Preparative methods for the synthesis of ethyl esters of 2,4-dichloro- and 2-oxo-4-chloroquinoline-3-carboxylic acids were developed.The behavior of the compounds indicated was studied under conditions of alkaline and acidic hydrolysis, in reactions with some nucleophilic reagents, as well as in reductive dehalogenation.Results of the study of the antimicrobial and antiinflammatory activity of the synthesized compounds are presented.
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