Journal of the Chemical Society. Perkin transactions I p. 1319 - 1323 (1980)
Update date:2022-07-30
Topics:
Jessep, Michael A.
Leaver, Derek
3H-Pyrrolizine reacts with NN-dimethylformamide and phosphoryl chloride to give a 3-(NN-dimethylaminomethylene)-3H,5H-pyrrolizinium salt (2), isolated as the perchlorate, which can be further converted, with NN-dimethylthioformamide and acetic anhydride, into 3,5-bis-(NN-dimethylaminomethylene)-3H,5H-pyrrolizinium perchlorate (8).The conjugate base of the salt (2) reacts with dimethyl but-2-yne-1,4-dioate to give dimethyl pyrrolo<2,1,5-cd>indolizine-5,6-dicarboxylate.The salt (8) reacts with nitromethane, in the presence of base, to give 6-nitropyrrolo<2,1,5-cd>indolizine (9a) and with ammonia to give pyrazino<2,1,6-cd>pyrrolizine (10a).Electrophilic substitution reactions of (9a) and (10a), and nucleophilic substitution of (10a), are described.
View MoreHANGZHOU PANYU CHEMICAL CO.,LIMITED
Contact:+86-571-86578491
Address:Rm 605, NO.1870 Binsheng Road,Binjiang Dist, Hangzhou, China
Lishui Nanming Chemical Co., Ltd(expird)
Contact:+86-0578-2134101，2697830
Address:No.19 Tongji Road Shuige Industrial zone
Contact:86 513 85512619
Address:Rm.1306, Building A, Wenfeng Mansion,168 Gongnong Road, Nantong Jiangsu China
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.
Contact:+86-512-6585 6968
Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China
Goldwills Pharmaceuticals Co., Ltd.
Contact:0916-2237889 13991621155
Address:North Suburb of Hanzhong city, Shaanxi Province
Doi:10.1080/00397910008087211
(2000)Doi:10.1139/v03-064
(2003)Doi:10.1039/b402794a
(2004)Doi:10.1016/S0040-4039(00)80222-1
(1988)Doi:10.1055/s-0028-1087935
(2009)Doi:10.1016/j.ejmech.2010.11.003
(2011)
