Journal of the Chemical Society. Perkin transactions I p. 1319 - 1323 (1980)
Update date:2022-07-30
Topics:
Jessep, Michael A.
Leaver, Derek
3H-Pyrrolizine reacts with NN-dimethylformamide and phosphoryl chloride to give a 3-(NN-dimethylaminomethylene)-3H,5H-pyrrolizinium salt (2), isolated as the perchlorate, which can be further converted, with NN-dimethylthioformamide and acetic anhydride, into 3,5-bis-(NN-dimethylaminomethylene)-3H,5H-pyrrolizinium perchlorate (8).The conjugate base of the salt (2) reacts with dimethyl but-2-yne-1,4-dioate to give dimethyl pyrrolo<2,1,5-cd>indolizine-5,6-dicarboxylate.The salt (8) reacts with nitromethane, in the presence of base, to give 6-nitropyrrolo<2,1,5-cd>indolizine (9a) and with ammonia to give pyrazino<2,1,6-cd>pyrrolizine (10a).Electrophilic substitution reactions of (9a) and (10a), and nucleophilic substitution of (10a), are described.
View MoreMS( MAOSHENG )Chemical CO.,LTD
Contact:+86-519-82726678.82726378
Address:TAOXI INDUSTRY ZONE JINTAN
Contact:+86-27-87204219, +86-27-87215023
Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Lyrin Industrial Corporation Limited
Contact:86-731-82571800
Address:Rm 2408,Asia Economy International Building,Shaoshan Road South,Yuhua District,Changsha,Hunan,China
website:http://www.acrospharmatech.com
Contact:+1-3234804688
Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong
Shangyu Sanhechemicals Co.,LTD.
Contact:86-0571-56696839
Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
Doi:10.1080/00397910008087211
(2000)Doi:10.1139/v03-064
(2003)Doi:10.1039/b402794a
(2004)Doi:10.1016/S0040-4039(00)80222-1
(1988)Doi:10.1055/s-0028-1087935
(2009)Doi:10.1016/j.ejmech.2010.11.003
(2011)
