4-Chloro-5H-1,2,3-dithiazol-5-one: A good α-thiocyanating agent for α,β-unsaturated β-amino esters

Article abstract of DOI:10.1016/S0040-4039(99)01235-6

Treatment of 4-chloro-5H- 1,2,3-dithiazol-5-one with 3-alkyl (or aryl)- 3-amino-2-propenoate esters in DMSO at 120°C gave the corresponding 2- thiocyanated esters 4 (major) and 5-alkoxycarbonyl-4-alkyl (or aryl)-4- thiazolin-2-ones 5 (minor), whereas the