Synthesis of [14C2]Taxol: Application of (+)/(-)-[13-14C(n)]BABS, part 3

DOI: 10.1002/(SICI)1099-1344(200002)43:2<169::AID-JLCR302>3.0.CO;2-6

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 169 - 176 (2000)

Update date:2022-07-29

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Authors:

Rodriguez

Voges Voges

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Article abstract of DOI:10.1002/(SICI)1099-1344(200002)43:2<169::AID-JLCR302>3.0.CO;2-6

A multiple step stereoselective procedure was successfully applied to doubly C-14 labelled Taxol 1 in its pharmacologically essential (2R,3S)N-benzoyl-3-phenylisoserine side chain. A highly stereocontrolled aldol reaction of internally developed (+)-[ View More

Full text of DOI:10.1002/(SICI)1099-1344(200002)43:2<169::AID-JLCR302>3.0.CO;2-6

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Product name:(3R,4S)-1-benzoyl-3-(tert-butyldimethylsilanyloxy)-4-phenyl-[2,3-14C₂]azetidin-2-one

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