Evaluation of rotenone and related compounds as antagonists of slow-reacting substance of anaphylaxis

DOI: 10.1021/jm00183a011

Source and publish data:

Journal of Medicinal Chemistry p. 1022 - 1026 (1980)

Update date:2022-08-05

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Authors:

Ashack Ashack

McCarty McCarty

Malek Malek

Goodman Goodman

Peet Peet

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Article abstract of DOI:10.1021/jm00183a011

Rotenone, dihydrorotenone, isorotenone, mutarotenone, and deguelin were found to be potent antagonists of slow-reacting substance of anaphylaxis (SRS-A) in vitro. However, these compounds were also shown to inhibit histamine, serotonin, and acetylcholine

Full text of DOI:10.1021/jm00183a011

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