Alkylation of pyrazolones via the mitsunobu reaction

DOI: 10.3987/COM-96-7657

Source and publish data:

Heterocycles p. 309 - 314 (1997)

Update date:2022-07-29

Topics:

Authors:

Holzer, Wolfgang

Plagens, Brigitte

Lorenz, Karin

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Article abstract of DOI:10.3987/COM-96-7657

The reaction of 3-methyl-1-phenyl-2-pyrazolin-5-one and 4-acyl derivatives thereof (R⁴ = COPh, 2-thienoyl, COCH₂CH₂Ph, COCH=CHPh) with various alcohols under 'Mitsunobu'-conditions was studied. In many cases selective O-alkylation could be achieved.

Full text of DOI:10.3987/COM-96-7657

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