Synthesis and Biological Activity of N6-(p-Sulfophenyl)alkyl and N6-Sulfoalkyl Derivatives of Adenosine: Water-Soluble and Peripherally Selective Adenosine Agonists

DOI: 10.1021/jm00100a020

Source and publish data:

Journal of Medicinal Chemistry p. 4143 - 4149 (1992)

Update date:2022-07-31

Topics:

Authors:

Jacobson, Kenneth A.

Nikodijevic, Olga

Ji, Xiao-duo

Berkich, Deborah A.

Eveleth, David

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00100a020

A series of N⁶-(p-sulfophenyl)alkyl and N⁶-sulfoalkyl derivatives of adenosine was synthesized, revealing that N⁶-(p-sulfophenyl)adenosine (10b) is a moderately potent (K_i vs <³H>PIA in rat cortical m

Full text of DOI:10.1021/jm00100a020

Products guided by the article

Product name:Benzenesulfonic acid, 4-(4-aminobutyl)-

Cas No:28988-45-6

R&D Labs maybe for 28988-45-6

Changchun BC＆HC Pharmaceutical Technology Co.,Ltd

Contact:+86-0431-80871588, +86-0431-80871788

Address:NO.668#Chuangxin road, Gaoxin District, Changchun ,Jilin
Qingdao XinYongAn Chemicals Co., Ltd

Contact:+86-532-81107967

Address:Chengyang dual-port industrial park by the sea，Qingdao
Shandong united-rising pharmaceutical cooperation.,ltd.

Contact:008653187965009

Address:171No., Jing5 Road, Shizhong District, Jinan, China
Phantom-pharma

Contact:

Address:
C-LAB Chemievermittlung GmbH

Contact:+49-9398-993127

Address:Untertorstr. 27

Relevant to this article

Rhodium catalysts bearing mixed thioether-phosphine ligands for carbonylation of methanol

Doi:10.1246/bcsj.82.1009
(2009)
Synthesis and antitumour activity of new derivatives of flavone-8-acetic acid (FAA). Part 4: Variation of the basic structure

Doi:10.1002/1521-4184(20006)333:6<181::AID-ARDP181>3.0.CO;2-O
(2000)
Doi:10.1021/jo00812a015
(1971)
Direct conversion of EPR dipolar time evolution data to distance distributions

Doi:10.1006/jmre.2001.2498
(2002)
Solid-phase synthesis of hydroxy-acids leading to macrolactones

Doi:10.1016/S0040-4039(00)00711-5
(2000)
Doi:10.1139/v57-141
(1957)

Article Doi