Synlett p. 2193 - 2196 (2007)
Update date:2022-08-05
Topics:
Gosselin, Francis
Britton, Robert A.
Mowat, Jeffrey
O'Shea, Paul D.
Davies, Ian W.
A chromatography-free synthesis of enantiomerically enriched chiral α-trifluoromethyl α-hydroxy acids prepared via an asymmetric (R)-BINOL-mediated organozincate addition to ethyl 2,2,2-trifluoropyruvate (1) is reported. Georg Thieme Verlag Stuttgart.
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