Synthesis and characterization of the antitumor activities of analogues of meridine, a marine pyridoacridine alkaloid

Article abstract of DOI:10.1021/jm0108496

Marine compounds with pyridoacridine skeletons are known to exhibit interesting antitumor activities. Among these compounds, meridine has already been reported as having significant antitumor activities in vitro. We synthesized 24 analogues of meridine su