Journal of labelled compounds and radiopharmaceuticals p. 917 - 924 (2000)
Update date:2022-08-05
Topics:
Kendall, John T.
An enantioselective synthesis of [2,3,3,2'3',5',6'-2H7]-L-tyrosine is described. Z-3-(4-acetoxy-2,3,5,6-2H4-phenyl)-3-2H-2-acetylamino acrylic acid was prepared in five steps from phenol-d6. Chiral reduction of the olefin followed by removal of the acetate protecting groups furnished the d7-amino acid in high ee.
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Doi:10.1055/s-2000-6411
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