α-Methylation of ketones via manganese-enolates: Absence of undesired polyalkylation

DOI: 10.1016/S0040-4039(00)60135-1

Source and publish data:

Tetrahedron Letters p. 7395 - 7398 (1993)

Update date:2022-08-05

Topics:

Authors:

Reetz, Manfred T.

Haning, Helmut

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60135-1

The transmetalation of ketone lithium-enolates using MnBr₂ generates manganese-enolates which react with CH₃I to provide α-methylated ketones with essentially no undesired polyalkylated byproducts.

Full text of DOI:10.1016/S0040-4039(00)60135-1

Products guided by the article

Product name:2,6-dimethyl-1-methoxy-1-cyclohexene

Cas No:30451-96-8

R&D Labs maybe for 30451-96-8

SINO GREAT ENTERPRISE LTD.

Contact:+86-731-84427351

Address:154 JIANXIANG SOUTH ROAD
Hotechem Shanghai Co., Ltd

Contact:13120882795；+86-21-34621078;+86-021-31122318

Address:Suite 2,No.2715 Longwu Road
Allright GC (Jinan) Biotechnology Ltd.

website:https://www.argcbiotech.com/

Contact:86-18405413579-

Address: No.27566 of Jingshiroad, Huaiyin District, Jinan City(250011), Shandong Province, China.
Zhejiang Linhai Xinhua Chemicals Factory

Contact:0086-13661858911

Address:Xunqiao Development Zone, Linhai, Zhejiang, China
Chongqing Shuangfeng Chemical Co.,Ltd

Contact:+86-23-49850156

Address:No.663,xuanhua Rd,yongchuan,chongqing,China

Relevant to this article

Doi:10.1039/J19710000562
()
Significantly improved method for the pd-catalyzed coupling of phenols with aryl halides: Understanding ligand effects

Doi:10.1002/anie.200601253
(2006)
A novel catalyst-free, eco-friendly, on water protocol for the synthesis of 2,3-dihydro-1H-perimidines

Doi:10.1016/j.tetlet.2019.150946
(2019)
On the complexity of kinetics and the mechanism of the thiosulfate- periodate reaction

Doi:10.1021/ic2006309
(2011)
Doi:10.1021/jm00327a020
(1965)
Doi:10.1021/jm00284a015
(1971)

Article Doi