α-Methylation of ketones via manganese-enolates: Absence of undesired polyalkylation

DOI: 10.1016/S0040-4039(00)60135-1

Source and publish data:

Tetrahedron Letters p. 7395 - 7398 (1993)

Update date:2022-08-05

Topics:

Authors:

Reetz, Manfred T.

Haning, Helmut

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60135-1

The transmetalation of ketone lithium-enolates using MnBr₂ generates manganese-enolates which react with CH₃I to provide α-methylated ketones with essentially no undesired polyalkylated byproducts.

Full text of DOI:10.1016/S0040-4039(00)60135-1

Products guided by the article

Product name:2,6-dimethyl-1-methoxy-1-cyclohexene

Cas No:30451-96-8

R&D Labs maybe for 30451-96-8

Hangzhou Sartort Biopharma Co., Ltd

website:http://www.sartort.com

Contact:86-571-87039693

Address:No. 57, Tech Park Road, Hangzhou, Zhejiang, China
wuxi huabin bio-tech Co.,Ltd(expird)

Contact:86-0510-85133006

Address:hubin road NO157
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD

Contact:+86-531-55696072

Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
Jiangsu Institute of Ecomones Co., Ltd

website:http://www.jsmone.com

Contact:+86-519-82821700

Address:95 Huanyuan N. Road, Jintan, Jiangsu, China
Zhengzhou Minzhong Pharmaceutical Co.,ltd

Contact:0086-371-65797115

Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China

Relevant to this article

Doi:10.1039/J19710000562
()
Significantly improved method for the pd-catalyzed coupling of phenols with aryl halides: Understanding ligand effects

Doi:10.1002/anie.200601253
(2006)
A novel catalyst-free, eco-friendly, on water protocol for the synthesis of 2,3-dihydro-1H-perimidines

Doi:10.1016/j.tetlet.2019.150946
(2019)
On the complexity of kinetics and the mechanism of the thiosulfate- periodate reaction

Doi:10.1021/ic2006309
(2011)
Doi:10.1021/jm00327a020
(1965)
Doi:10.1021/jm00284a015
(1971)

Article Doi