Journal of labelled compounds and radiopharmaceuticals p. 1095 - 1105 (2000)
Update date:2022-08-03
Topics: Animal Studies Elimination Regulatory Approval Toxicity Studies Pharmacokinetics and Pharmacodynamics Metabolism Human Studies
McEvoy Egan
Dean
Marks
Song, Zhiguo
Melillo
A carbon-14 labeled version of the ascomycin analog 1, a potential new immunosuppressant agent, was synthesized for utilization in animal and human drug metabolism studies. In order to place the carbon-14 label at a metabolically stable position, it was n
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