Synthesis of the novel amino acid 4-amino-3-(aminomethyl)benzoic acid (AmAbz) and its protected derivatives as building blocks for pseudopeptide synthesis

Article abstract of DOI:10.1002/1099-0690(200011)2000:22<3755::aid-ejoc3755>3.0.co;2-i

4-Amino-3-(aminomethyl)benzoic acid (1) (AmAbz) is a novel unnatural amino acid with promise in applications as a building block for the synthesis of peptidomimetics and as a scaffold for combinatorial chemistry. It was efficiently synthesized in three st