
Phosphorus, Sulfur and Silicon and the Related Elements p. 153 - 169 (2000)
Update date:2022-07-30
Radwan
Saponification of ethyl 3-amino-4,5-diphenylthieno[2,3-c]pyridazine-2-carboxyate (1) with alcoholic sodium hydroxide, followed by acidification, afforded the corresponding acid 2. Also, reaction of 1 with ethanolamine and formamide, respectively, gave compounds 5 and 6. Compound 2 reacts with orthophosphoric acid under different conditions to give some new thieno[2,3-c] pyridazine derivatives 3 and 4, which were subjected to reactions to produce compounds 7-18. Furtheremore, compounds 5 and 6 were used to synthesize some substituted pyrimido[4′,5′:4,5)-thieno[2,3-c]pyridazine derivatives 21-30.
View MoreJiangsu Fengshan Group Co., Ltd.
Contact:86-25-86558671
Address:1903,Central International Mansion 105-6 North Zhongshan Road, Nanjing, China
Shandong united-rising pharmaceutical cooperation.,ltd.
Contact:008653187965009
Address:171No., Jing5 Road, Shizhong District, Jinan, China
Contact:17316303296
Address:240 Amboy Ave
Contact:+1 (647) 918 5848
Address:2343 BRIMLEY RD., Suite 250
Anhui Qingyun Pharmaceutical and Chemical Co.,Ltd
Contact:+86-551-63633067
Address:Shuangfeng Road Hefei Anhui
Doi:10.1016/0040-4020(66)80012-1
(1966)Doi:10.1021/jm00261a028
(1973)Doi:10.1021/jo01303a039
(1980)Doi:10.1016/S0040-4039(00)01452-0
(2000)Doi:10.1080/00397911.2021.1953532
(2021)Doi:10.1021/acs.orglett.7b00958
(2017)