Synthetic Communications p. 1678 - 1687 (2018)
Update date:2022-08-05
Topics:
Heo, Hoon Gu
Yu, Jin
Jillella, Raveendra
Oh, Chang Ho
A series of novel pyrazolo pyrimidinone derivatives (3(a–d), 4(a–d), and 6(a–d)) was synthesized from various pyrazolo amides (2a–d) which are synthesized by the reaction between ethyl 5-amino-3-methyl-1-phenyl-1H-pyrazole-4-carboxylate (1) and various lithium amides. In addition, we also described the synthesis of sclerotigenin drug molecule which has quinazoline moiety from simple 2-nitro benzoic acid with high yields.
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