
Chemistry of Heterocyclic Compounds p. 56 - 59 (1994)
Update date:2022-08-04
Topics:
Sipyagin, A. M.
Pal'tsun, S. V.
Pomytkin, I. A.
Aleinikov, N. N.
The reaction on 2,3,5,6-tetrachloro-4-trifluoromethylthiopyridine with various nucleophilic reagents has been studied.It was shown that CF3S group is readily replaced under the action of O- and S-nucleophiles.Competition was detected between replacement of an α-chlorine atom on the pyridine ring and of the fluorine-containing group under the action of N-nucleophilic reagents.New derivatives of trichlorotrifluoromethylthiopyridine with nitrogen-containing substituents have been synthesized.
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