Cytostatic 6-arylpurine nucleosides III. Synthesis and structure-activity relationship study in cytostatic activity of 6-aryl-, 6-hetaryl-and 6-benzylpurine ribonucleosides

Article abstract of DOI:10.1135/cccc20010483

A series of fifteen 6-aryl-, 6-hetaryl-and 6-benzylpurine ribonucleosides has been prepared by Pd-catalyzed cross-coupling reactions of 6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-purine with arylboronic acids, hetarylzinc halides, hetarylstannanes