Tetrahedron Letters p. 3807 - 3809 (2001)
Update date:2022-08-02
Topics:
Luo, Yue
Evindar, Ghotas
Fishlock, Dan
Lajoie, Gilles A
Two efficient and convenient syntheses of N-Cbz and N-Fmoc N-methyl serine and threonine are described. The amino acid side-chain alcohol can be protected as a TBDMS ether in very good yield or left free, followed by the formation and subsequent reduction of the corresponding oxazolidinone.
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