Metalated aromatic carboxylic acids: Improved synthesis of SDZ HUL412

Article abstract of DOI:10.1080/00397919508011404

Synthesis of aryl methyl ester 2 is described utilizing a metalation-condensation and a metalation-alkylation sequence starting from the dianion of p-toluic acid generated in an aprotic solvent medium.

Full text of DOI:10.1080/00397919508011404

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Synthetic Communications:
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Metalated Aromatic
Carboxylic Acids: Improved
Synthesis of SDZ HUL412
John C. Amedio Jr. a , Ustun B. Sunay a & Oljan
Repic a
a Chemical Research & Development, Technical
R & D , Sandoz Research Institute, Sandoz
Pharmaceutical Corporation , Route 10, East
Hanover, New Jersey, 07936, USA
Published online: 23 Sep 2006.
To cite this article: John C. Amedio Jr. , Ustun B. Sunay & Oljan Repic (1995)
Metalated Aromatic Carboxylic Acids: Improved Synthesis of SDZ HUL412,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 25:5, 667-680, DOI: 10.1080/00397919508011404
To link to this article: http://dx.doi.org/10.1080/00397919508011404
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