Bioorganic and Medicinal Chemistry Letters p. 1061 - 1064 (1998)
Update date:2022-08-02
Topics:
Aneja, Sarla G.
Ivanova, Pavlina T.
Aneja, Rajindra
An approach to synthesis of 2-modified phosphatidylinositol-4,5- bisphosphates, which are substrate analogues useful as probes and modulators of the PI-PLC enzyme family, is described and illustrated for the dibutyl-2- deoxy-2-fluoro analogue, a probe designed for delineating substrate and PI- PLC interactions by X-ray crystallography.
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