PALLADIUM-CATALYZED REGIO- AND STEREOSELECTIVE DESULFONYLATION OF ALLYLIC SULFONES WITH LiHBEt3. APPLICATION TO THE SYNTHESIS OF SQUALENE

Article abstract of DOI:10.1246/cl.1985.451

Allylic p-tolyl sulfones were easily desulfonylated to the corresponding alkenes by LiHBEt3 in the presence of a catalytic amount of under mild conditions with the preservation of the original stereochemistry.This reaction was successfully applied to the synthesis of squalene.