Separation of Silylated Oxime Isomers by High Resolution Gas Chromatography

Article abstract of DOI:10.1246/bcsj.67.1740

The stereoisomers of 2-butanone O-trimethylsilyloxime were observed as separate peaks, the intensity ratio being 1:3, by high resolution GC equipped with a capillary column. The peak with intensity 3 was assigned to the Z isomer of oxime bond and the intensity ratio corresponded to the stereoisomer ratio of 2-butanone oxime. Silanes including plural oxime groups also gave separate stereoisomer peaks corresponding to the isomer ratio of 2-butanone oxime.