Bioorganic and Medicinal Chemistry Letters p. 1863 - 1865 (2005)
Update date:2022-08-03
Topics:
Zarghi, Afshin
Tabatabai, Sayyed A.
Faizi, Mehrdad
Ahadian, Avideh
Navabi, Parisa
Zanganeh, Vahideh
Shafiee, Abbas
A series of new 2-substituted-5-(2-benzyloxyphenyl)-1,3,4-oxadiazoles have been synthesized and evaluated as anticonvulsant agents. Compound 4b shows considerable anticonvulsant activity both in PTZ and MES models. It seems this effect is mediated through benzodiazepine receptors mechanism.
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Doi:10.14233/ajchem.2020.22454
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