Bioorganic and Medicinal Chemistry Letters p. 2509 - 2513 (2009)
Update date:2022-08-03
Topics:
Van der Walt, Elizna M.
Milczek, Erika M.
Malan, Sarel F.
Edmondson, Dale E.
Castagnoli Jr., Neal
Bergh, Jacobus J.
Petzer, Jacobus P.
Previous studies have shown that (E)-8-(3-chlorostyryl)caffeine (CSC) is a specific reversible inhibitor of human monoamine oxidase B (MAO-B) and does not bind to human MAO-A. Since the small molecule isatin is a natural reversible inhibitor of both MAO-B
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