Journal of the American Chemical Society p. 370 - 387 (2019)
Update date:2022-08-15
Topics:
Van Loo, Bert
Bayer, Christopher D.
Fischer, Gerhard
Jonas, Stefanie
Valkov, Eugene
Mohamed, Mark F.
Vorobieva, Anastassia
Dutruel, Celine
Hyv?nen, Marko
Hollfelder, Florian
Highly proficient, promiscuous enzymes can be springboards for functional evolution, able to avoid loss of function during adaptation by their capacity to promote multiple reactions. We employ a systematic comparative study of structure, sequence, and sub
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