Organic Letters p. 3879 - 3882 (2018)
Update date:2022-08-03
Topics:
Meisel, Joseph W.
Hu, Chunhua T.
Hamilton, Andrew D.
The design and characterization of a proteomimetic foldamer that displays lateral flexibility endowed by intramolecular bifurcated hydrogen bonds is reported. The MAMBA scaffold, derived from meta-aminomethylbenzoic acid, adopts a serpentine conformation that mimics the side chain projection of all four residues in a β-hairpin turn.
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