Synthese de N-alkyl tetrahydro-2,3,6,7 azepines et de N-alkyl hexahydro-1,2,3,4,7,8 azocines a partir d'ω-monoalkylaminoallyltrimethylsilanes par processus d'aminomethylation-desilylation intramoleculaire

Article abstract of DOI:10.1016/0022-328X(90)80253-V

In acidic medium, the ω-monoalkylaminoallyltrimethylsilanes RNH(CH2)nCH-(SiMe3)CH=CH2 (n=2, 3) regiospecifically react with formaldehyde, by an intramolecular process, to give alkenyl nitrogen-containing heterocycles, such as N-alkyl-2,3,6,7-tetrahydroaze