Monocyclopentadienyltitanium aryloxide complexes: Preparation, characterization, and application in cyclization reactions

Article abstract of DOI:10.1021/om010755u

A variety of monocyclopentadienyltitanium aryloxide complexes were prepared, characterized by X-ray crystallography, and used to catalyze or mediate cyclization reactions. Structural characterization allowed for the comparison of steric parameters of various 2,6-disubstituted aryloxide ligands. Transformations of dienes and enynes - including the catalysis of a 1,6-diene cycloisomerization and the intramolecular Pauson - Khand reaction - were investigated. A titanium metallacycle was prepared from a sterically hindered enyne containing a trisubstituted olefin. The Pauson - Khand reaction of trimethylsilyl-substituted enynes was promoted to generate α-silylcyclopentenones.