Synthesis of partially modified retro-inverso substance P analogues and their biological activity

Article abstract of DOI:10.1021/jm00356a003

Partial retro-inverso modification of a single peptide bond was applied to pGlu-Phe-Phe-Gly-Leu-Met-NH₂ (I), a C-terminal hexapeptide analogue of the neuropeptide substance P. Two analogues with reversed peptide bonds, between the pGlu-Phe and