Tetrahedron Letters p. 4235 - 4238 (1997)
Update date:2022-07-29
Topics:
Ojika, Makoto
Yoshino, Go
Sakagami, Youji
Two ceramide 1-sulfates 1 and 2 have been isolated from the Japanese Bryozoa Watersipora cucullata as new potent inhibitors of a human DNA topoisomerase I. The gross structures of 1 and 2 were determined by spectroscopic analysis, and their absolute stereochemistry was elucidated by the optical data of degradation products.
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