Journal of Medicinal Chemistry p. 1203 - 1210 (2002)
Update date:2022-07-30
Topics:
Xu, Lifen
Izenwasser, Sari
Katz, Jonathan L.
Kopajtic, Theresa
Klein-Stevens, Cheryl
Zhu, Naiju
Lomenzo, Stacey A.
Winfield, Leyte
Trudell, Mark L.
A series of eight 2-substituted 3-tolyltropane derivatives were synthesized, and the in vitro and in vivo biological activities as dopamine uptake inhibitors were determined. From the in vitro structure-activity data, it is apparent that a tolyl group in
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