Regioselective oxidation of azidodiols, bromodiols and triol derivatives by dimethyldioxirane

Article abstract of DOI:10.1016/S0040-4020(98)00885-0

Azidodiols, bromodiols and triol derivatives were regioselectively monooxidised to the corresponding ketols using dimethyldioxirane. This regioselectivity is essentially determined by dipolar functionalities close to the potential reactive carbinol. These results make the reactivity of polyols with dimethyldioxirane highly predictable.