Chemistry of Heterocyclic Compounds p. 672 - 675 (1984)
Update date:2022-07-29
Topics:
Groszkowski, S.
Krezhel, I.
Kozycka, L.
S-Alkylation products are formed in the reaction of tetrahydropyrimidine-2-thione and hexahydro-1,3-diazepine-2-thione with chloroacylpiperazines in dimethylformamide at room temperature; dihydrothiazolo<3,2-a>pyrimidine and tetrahydrothiazolo<3,2-a>-<1,3>diazepine systems are obtained in refluxing ethanol.It is shown that the S-alkyl derivatives are very readily converted to condensed systems.
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