Synthetic Communications p. 785 - 790 (2005)
Update date:2022-08-04
Topics:
Valizadeh, Hassan
Mamaghani, Manouchehr
Badrian, Abed
The effect of microwave irradiation on the condensation reactions of arylaldehydes 1 and active methylene compounds 2 in aqueous media was studied and compared with "classical" conditions. The results show that the condensation was carried out only under microwave irradiation in the presence of ammonium chloride as a catalyst, followed by dehydration, to afford (E)-olefins 3. The protocol was used to synthesize coumarins by a condensation reaction of salicylaldehyde or its derivatives with various derivatives of ethylacetate 5 (e.g., R3CH2CO2Et; R3: CO 2Et, CO2Me, COMe, CN) in high yields. These investigations will contribute to the development of environmentally friendly and inexpensive processes in organic synthesis.
View MoreJiangxi Hito Chemical Co., Ltd.
Contact:+86-792-3170318
Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
Contact:86-15588110016
Address:LINYI CITY,SHANDONG PROVINCE,CHINA
Contact:+86-519-86623222
Address:29F/D, 99 Yanling West Road, Changzhou, Jiangsu, China
Zhejiang Tianyu Pharmaceutical Co., Ltd.
Contact:+86-576-84177669, 89189665,89189688,84168770
Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Contact:86-10-62983737; +86-10-51287608
Address:4/F Building C, 2 Shangdi Xinxi Road
Doi:10.1021/ja01317a046
(1934)Doi:10.1023/A:1015012302947
(2001)Doi:10.1021/ja01555a050
(1958)Doi:10.1021/jo020083x
(2002)Doi:10.1006/jssc.2001.9166
(2001)Doi:10.1016/j.cclet.2013.11.027
(2014)