Asymmetric Horner-Wadsworth-Emmons reactions with Meso-dialdehydes: Scope, mechanism, and synthetic applications

Article abstract of DOI:10.1080/10426509908546209

Asymmetric Homer-Wadsworth-Emmons reactions between chiral phosphonate reagents and various meso-dialdehydes have been investigated. A mechanistic model useful for rationalizing the experimentally observed stereoselectivities is presented. Furthermore, st

Full text of DOI:10.1080/10426509908546209

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Phosphorus, Sulfur, and
Silicon and the Related
Elements
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Asymmetric Horner-
Wadsworth-Emmons
Reactions with Meso-
Dialdehydes: Scope,
Mechanism, and
Synthetic Applications
Tobias Rein , Lauri Vares , Ikuo
Kawasaki , Torben M. Pedersen , Per-Ola
Norrby , Peter Brandt & David Tanner
a Department of Organic Chemistry ,
Technical University of Denmark , Lyngby
DK-2800, Denmark
b Department of Organic Chemistry ,
Technical University of Denmark , Lyngby
DK-2800, Denmark
c Department of Organic Chemistry ,
Technical University of Denmark , Lyngby
DK-2800, Denmark
d Department of Organic Chemistry ,
Technical University of Denmark , Lyngby
DK-2800, Denmark
e Department of Medicinal Chemistry ,
Royal Danish School of Pharmacy,

Universitetsparken , 2, DK-2100
Copenhagen, Denmark
f Department of Chemistry , Organic
Chemistry, Royal Institute of Technology ,
S-10044 Stockholm, Sweden
g Department of Organic Chemistry ,
Technical University of Denmark , Lyngby
DK-2800, Denmark
Published online: 17 Mar 2008.
To cite this article: Tobias Rein , Lauri Vares , Ikuo Kawasaki ,
Torben M. Pedersen , Per-Ola Norrby , Peter Brandt & David Tanner
(1999) Asymmetric Horner-Wadsworth-Emmons Reactions with Meso-
Dialdehydes: Scope, Mechanism, and Synthetic Applications, Phosphorus,
Sulfur, and Silicon and the Related Elements, 144:1, 169-172, DOI:
10.1080/10426509908546209
To link to this article: http://dx.doi.org/10.1080/10426509908546209
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