Bioorganic and Medicinal Chemistry Letters p. 5978 - 5981 (2006)
Update date:2022-09-26
Topics:
Feng, Dennis
Fisher, Michael
Liang, Gui-Bai
Qian, Xiaoxia
Brown, Chris
Gurnett, Anne
Leavitt, Penny Sue
Liberator, Paul A.
Mathew, John
Misura, Andrew
Samaras, Samantha
Tamas, Tamas
Schmatz, Dennis M.
Wyvratt, Matthew
Biftu, Tesfaye
Compounds 10a-10d and 10i are very potent inhibitors of Eimeria tenella cGMP-dependent protein kinase (0.081-0.32 nM) and are very efficacious antiparasitic agents in vivo when administered to chickens at 12.5-25 ppm levels in the feed.
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